Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease.

Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease.

BACKGROUNDThe pathophysiology and final result of meningococcal septic shock is intently related to the plasma stage of N. meningitidis lipopolysaccharides (LPS, endotoxin) and the circulating stage of meningococcal DNA. The purpose of the current examine was to quantify the variety of N. meningitidis in numerous formalin-fixed, paraffin-embedded (FFPE) tissue samples and contemporary frozen (FF) tissue … Read more