Veni, vidi, vici: the success of wtf meiotic drivers in fission yeast.

Meiotic drivers are selfish DNA loci that can bias their own transmission into gametes. Owing to their transmission advantages, meiotic drivers can spread in populations even if the drivers or linked variants decrease organismal fitness. Meiotic drive was first formally described in the 1950s and is thought to be a powerful force shaping eukaryotic genomes.

Classic genetic analyses have detected the action of meiotic drivers in plants, filamentous fungi, insects and vertebrates. Several of these drive systems have limited experimental tractability and relatively little is known about the molecular mechanisms of meiotic drive.

Recently, however, meiotic drivers were discovered in a yeast species. The Schizosaccharomyces pombe wtf gene family contains several active meiotic drive genes. This review summarizes what is known about the wtf family and highlights its potential as a highly tractable experimental model for molecular and evolutionary characterization of meiotic drive.

KT 5823
B6673-.1 100 µg
EUR 190.00

KT 5823
B6673-.25 250 µg
EUR 361.00

KT 5720
B9002-.05 50 µg
EUR 145.00

KT 5720
B9002-.1 100 µg
EUR 232.00

KT 5720
B9002-.25 250 µg
EUR 483.00

KT 5720
B9002-.5 500 µg
EUR 818.00

PST- KT
PVT11358 2 ug
EUR 370.00

Plasminogen Receptor (KT) (PLGRKT) Antibody
20-abx318476
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

KT 5823 (PKG kinase inhibitor)
SIH-458-100UG 100 µg
EUR 205.00
  • KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
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Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

KT 5823 (PKG kinase inhibitor)
SIH-458-500UG 500 µg
EUR 569.00
  • KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
  • Show more
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

Slc16a3 antibody
70R-8575 50 ug
EUR 467.00
Description: Affinity purified rabbit polyclonal Slc16a3 antibody

SMAD1/5 antibody
10R-8575 100 ul
EUR 393.00
Description: Mouse monoclonal SMAD1/5 antibody

IZUMO1 Blocking Peptide
33R-8575 100 ug
EUR 180.00
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of IZUMO1 antibody, catalog no. 70R-7523

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
GA-E0451RT-48T 48T
EUR 317.00

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
GA-E0451RT-96T 96T
EUR 496.00

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
QY-E11201 96T
EUR 361.00

Mouse Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt
QY-E20317 96T
EUR 361.00

Mouse RANKL ELISA Kit
55R-MRANKL-KT 1 kit
EUR 658.00
Description: ELISA kit for detection of Mouse RANKL in the research laboratory

VWF Antibody Pair
55R-VWF-KT 5 plates
EUR 775.00
Description: VWF antigen Matched Pair antibody Set for ELISA

Factor XI Antibody Pair
55R-FAC11-KT 5 plates
EUR 745.00
Description: Factor XI antigen Matched Pair antibody Set for ELISA

Factor IX Antibody Pair
55R-FAC9-KT 5 plates
EUR 760.00
Description: Factor IX antigen Matched Pair antibody Set for ELISA

Fibrinogen Matched Pair antibody Set
55R-FIBRINO-KT set
EUR 833.00
Description: Fibrinogen Matched Pair antibody Set for detection of Human Fibrinogen in the research laboratory